Sébastien Février, scientist at XLIM (CNRS/Universit é de Limoges), and his group showed that a bench-top, optical fibre-based laser source can be utilized to carry out infrared spectromicroscopy with an accuracy measuring up to, and in some concerns even exceeding, that of experiments at massive synchrotron centers.
Synchrotrons are accelerator centers that supply effective infrared light utilized for evaluating the chemical material of biological tissues with micrometer scale resolution. This high accuracy chemical imaging strategy allows an early medical diagnosis of pathologies such as cirrhosis and cancer. Nevertheless, already, the really high expense of ownership and restricted schedule of synchrotron sources has actually impeded the release of chemical imaging strategy in the health center.
Changing the synchrotron with a compact laser source might release the capacity of this strategy and relieve its application in the health center, hence speeding up access to medical diagnosis and treatment.
The outcomes were released in Optica, a global peer-reviewed journal committed to advanced research study in photonics.
The presentation included a consortium consisting of scientists from XLIM and the synchrotron Soleil in Saclay in addition to engineers from the business Novae, a start-up established in 2013 by scientists from the University of Limoges. Novae targets commercial and clinical markets such as laser-based bio-imaging and products micro-processing. The infrared laser is now part of Novae’s portfolio of items.
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Manli Wang et al. Synchrotron radiation-based Fourier-transform infrared spectromicroscopy for characterization of the protein/peptide circulation in single microspheres, Acta Pharmaceutica Sinica B(2015). DOI: 10.1016/ j.apsb.201503008